SEMA4B Protein, Mouse, Recombinant (His)

Item number	Size	Manual	Delivery time	Price
TGM-TMPK-01034-100ug	100 µg	-	7 - 10 business days*	392.00€
TGM-TMPK-01034-500ug	500 µg	-	7 - 10 business days*	1,571.00€
TGM-TMPK-01034-1mg	1 mg		7 - 10 business days*	2,643.00€

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Description: Semaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC)... more

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Product information "SEMA4B Protein, Mouse, Recombinant (His)"

Description: Semaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC) through PI3K-dependent suppression of MMP9 activation. SEMA4B may induce FoxO1 nuclear retention through suppressing PI3K/Akt signaling pathway, which subsequently inhibited cell growth through the direct nuclear target of FoxO1, p21. A role of SEMA4B in suppressing NSCLC growth, besides its role in inhibiting cell metastasis, and highlights SEMA4B as a promising therapeutic target for NSCLC.

Keywords:	Semaphorin-4B, MGC131831, KIAA1745, SEMAC, SEMA4B, SemC, Semaphorin-C
Supplier:	TargetMol
Supplier-Nr:	TMPK-01034

Properties

Conjugate:	No
MW:	75.7 kD

Database Information

KEGG ID :	K06521 \| Matching products
UniProt ID :	Q62179 \| Matching products
Gene ID :	GeneID 20352 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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