SEMA4B, His, Human

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z05802-100	100 µg		-		Request delivery time estimate		430.00€
GSC-Z05802-500	500 µg		-		Request delivery time estimate		1,425.00€

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Semaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC) through... more

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Product information "SEMA4B, His, Human"

Semaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC) through PI3K-dependent suppression of MMP9 activation. SEMA4B may induce FoxO1 nuclear retention through suppressing PI3K/Akt signaling pathway, which subsequently inhibited cell growth through the direct nuclear target of FoxO1, p21. A role of SEMA4B in suppressing NSCLC growth, besides its role in inhibiting cell metastasis, and highlights SEMA4B as a promising therapeutic target for NSCLC.

Keywords:	SEMA4B, Semaphorin-C, Semaphorin-4B
Supplier:	GenScript
Supplier-Nr:	Z05802

Properties

Conjugate:	No
Species reactivity:	human
MW:	75.8 kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

KEGG ID :	K06521 \| Matching products
UniProt ID :	Q9NPR2 \| Matching products
Gene ID :	GeneID 10509 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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