SASH1 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-6485.20	20 µg	-	-	-	Request delivery time estimate		90.00€
ABS-PP-6485.100	100 µg	-	-	-	Request delivery time estimate		180.00€

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Protein function: Is a positive regulator of NF-kappa-B signaling downstream of TLR4 activation.... more

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Product information "SASH1 (human), recombinant protein"

Protein function: Is a positive regulator of NF-kappa-B signaling downstream of TLR4 activation. It acts as a scaffold molecule to assemble a molecular complex that includes TRAF6, MAP3K7, CHUK and IKBKB, thereby facilitating NF-kappa-B signaling activation (PubMed:23776175). Regulates TRAF6 and MAP3K7 ubiquitination (PubMed:23776175). Involved in the regulation of cell mobility (PubMed:23333244, PubMed:23776175, PubMed:25315659). Regulates lipolysaccharide (LPS)-induced endothelial cell migration (PubMed:23776175). Is involved in the regulation of skin pigmentation through the control of melanocyte migration in the epidermis (PubMed:23333244). [The UniProt Consortium]

Keywords:	SAM and SH3 domain-containing protein 1, Proline-glutamate repeat-containing protein, Recombinant Human SASH1 Protein
Supplier:	Absea
Supplier-Nr:	PP-6485

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	13.5 kD
Format:	Solution

Database Information

KEGG ID :	K23705 \| Matching products
UniProt ID :	O94885 \| Matching products
Gene ID :	GeneID 23328 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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