SARS PrEST Antigen

SARS PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST70299.100 100 µl - -

3 - 8 business days*

264.00€
 
Protein function: Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine... more
Product information "SARS PrEST Antigen"
Protein function: Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser) (PubMed:22353712, PubMed:24095058, PubMed:9431993, PubMed:26433229, PubMed:28236339). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (PubMed:9431993, PubMed:26433229, PubMed:28236339). In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC (PubMed:24940000). Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at 'Lys-16' (H4K16). Thereby, inhibits the production of VEGFA and sprouting angiogenesis mediated by VEGFA (PubMed:19423848, PubMed:19423847, PubMed:24940000). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: SARS, SerRS, Seryl-tRNA synthetase, Seryl-tRNA(Ser/Sec) synthetase, Serine--tRNA ligase, cytoplasmic
Supplier: Atlas Antibodies
Supplier-Nr: APrEST70299

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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