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Product information "SAMD8 (human), recombinant protein"
Protein function: Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway. [The UniProt Consortium]
Keywords:
Sphingomyelin synthase-related protein 1, SMSr, Ceramide phosphoethanolamine synthase, CPE synthase, Sterile alpha motif domain-containing protein 8, SAM domain-containing protein 8, Recombinant Human SAMD8 Protein
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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