SAFB (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-11095-L.20	20 µg		-	-	Request delivery time estimate		115.00€
ABS-PP-11095-L.100	100 µg		-	-	Request delivery time estimate		205.00€

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Protein function: Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular... more

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Product information "SAFB (human), recombinant protein"

Protein function: Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (PubMed:9671816). Functions as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription (PubMed:12660241). Thereby acts as a negative regulator of cell proliferation (PubMed:12660241). When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter. [The UniProt Consortium]

Keywords:	Scaffold attachment factor B1, SAF-B, SAF-B1, HSP27 estrogen response element-TATA box-binding protein, HSP27 ERE-TATA-binding protein, Recombinant Human SAFB Protein
Supplier:	Absea
Supplier-Nr:	PP-11095-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	14 kD
Format:	Lyophilized

Database Information

UniProt ID :	Q15424 \| Matching products
Gene ID :	GeneID 6294 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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