RUVBL1 Protein, Human, Recombinant (His)

RUVBL1 Protein, Human, Recombinant (His)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-TMPY-03263-100ug 100 µg -

7 - 10 business days*

699.00€
 
Description: RUVBL1, also known as RVB1, is a component of the NuA4 histone acetyltransferase... more
Product information "RUVBL1 Protein, Human, Recombinant (His)"
Description: RUVBL1, also known as RVB1, is a component of the NuA4 histone acetyltransferase complex and belongs to the RuvB family. RUVBL1 is ubiquitously expressed with high expression in heart, skeletal muscle and testis. It possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. RUVBL1 is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. RUVBL1 plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex. It also is essential for cell proliferation. RUVBL1 may be able to bind plasminogen at cell surface and enhance plasminogen activation.
Keywords: ECP54, TIH1, RuvB-like AAA ATPase 1, TIP49, Pontin52, NMP238, TIP49A, PONTIN, INO80H, RVB1
Supplier: TargetMol
Supplier-Nr: TMPY-03263

Properties

Conjugate: No
MW: 52.4 kD

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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