RSPO4 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-12137-L.20	20 µg		-	-	Request delivery time estimate		115.00€
ABS-PP-12137-L.100	100 µg		-	-	Request delivery time estimate		205.00€

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Protein function: Activator of the canonical Wnt signaling pathway by acting as a ligand for... more

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Product information "RSPO4 (human), recombinant protein"

Protein function: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors (PubMed:29769720). Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin- dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway (PubMed:21727895, PubMed:21909076). [The UniProt Consortium]

Keywords:	R-spondin-4, Roof plate-specific spondin-4, hRspo4, Recombinant Human RSPO4 Protein
Supplier:	Absea
Supplier-Nr:	PP-12137-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	11.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K23099 \| Matching products
UniProt ID :	Q2I0M5 \| Matching products
Gene ID :	GeneID 343637 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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