RNF40 PrEST Antigen

RNF40 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST82122.100 100 µl - -

3 - 8 business days*

264.00€
 
Protein function: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates... more
Product information "RNF40 PrEST Antigen"
Protein function: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: BRE1B, RNF40, RBP95, BRE1-B, RING finger protein 40, E3 ubiquitin-protein ligase BRE1B, RING-type E3 ubiquitin transferase BRE1B, 95 kDa retinoblastoma-associated protein
Supplier: Atlas Antibodies
Supplier-Nr: APrEST82122

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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