RNF157 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-6772-L.20	20 µg	-	-	-	10 - 15 business days*		115.00€
ABS-PP-6772-L.100	100 µg	-	-	-	10 - 15 business days*		205.00€

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Protein function: E3 ubiquitin ligase that ubiquitinates APBB1 for its degradation by the... more

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Product information "RNF157 (human), recombinant protein"

Protein function: E3 ubiquitin ligase that ubiquitinates APBB1 for its degradation by the proteasome and thus prevents apoptosis and promotes survival of neurons (PubMed:25342469). Has a dual role in neurons as it is also required for dendrite growth and maintenance for which its ligase activity is not critical (PubMed:25342469). May act as a scaffold molecule to regulate this process (PubMed:25342469). Acts as a downstream effector of the interconnected PI3K and MAPK signaling pathways and thus participates in the regulation of the cell cycle (PubMed:28655764). [The UniProt Consortium]

Keywords:	E3 ubiquitin ligase RNF157, RING finger protein 157, RING-type E3 ubiquitin transferase RNF157, Recombinant Human RNF157 Protein
Supplier:	Absea
Supplier-Nr:	PP-6772-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	24.5 kD
Format:	Lyophilized

Database Information

UniProt ID :	Q96PX1 \| Matching products
Gene ID :	GeneID 114804 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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