RNase Inhibitor, Murine

RNase Inhibitor, Murine (rmRnh1) is a 50 kDa recombinant protein of mouse origin. This RNase inhibitor specifically inactivates a wide spectrum of RNases, including RNase A, RNase B and C. For example, rmRnh1 (20 U/ 20 µl reaction) inhibits up to 1 ng RNase A (Figure 1). It is not effective against RNase T1, S1 Nuclease, RNase H or RNase from Aspergillus. It can be used in applications where RNases could be a potential problem, for example, RT-PCR, cDNA synthesis, in vitro transcription, and enzymatic RNA labeling reaction. The inhibitor does not interfere with enzymes commonly used to prepare or analyze RNA, such as, Taq DNA Polymerase, Phage RNA Polymerases, or M-MuLV reverse transcriptase.