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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| TGM-TMPY-04770-50ug | 50 µg | - |
7 - 10 business days* |
433.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: RIOK1, also known as RIO kinase 1, is a member of the RIO family of atypical serine... more
Product information "RIOK1 Protein, Human, Recombinant (His & GST)"
Description: RIOK1, also known as RIO kinase 1, is a member of the RIO family of atypical serine protein kinases first characterized in yeast. RIOK1 and RIOK2 proteins are present in organisms from Archaea to humans. RIOK1 functions as a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity. RioK1 and pICln bind to PRMT5 in a mutually exclusive fashion. This results in a PRMT5-WD45/MEP5 core structure that either associates with pICln or RioK1 RIOK1 in distinct complexes. RIOK1 functions in analogy to pICln as an adapter protein by recruiting the RNA-binding protein nucleolin to the PRMT5 complex for its symmetrical methylation.
| Keywords: | AD034, bA288G3.1, RIO kinase 1, RRP10 |
| Supplier: | TargetMol |
| Supplier-Nr: | TMPY-04770 |
Properties
| Conjugate: | No |
| MW: | 93.4 kD |
Database Information
| KEGG ID : | K07178 | Matching products |
| UniProt ID : | Q9BRS2 | Matching products |
| Gene ID : | GeneID 83732 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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