RING1 PrEST Antigen

RING1 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST70894.100 100 µl - -

7 - 10 business days*

264.00€
 
Protein function: Constitutes one of the E3 ubiquitin-protein ligases that mediate... more
Product information "RING1 PrEST Antigen"
Protein function: Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: RNF1, RING1, EC=2.3.2.27, RING finger protein 1, Polycomb complex protein RING1, E3 ubiquitin-protein ligase RING1, Really interesting new gene 1 protein, RING-type E3 ubiquitin transferase RING1
Supplier: Atlas Antibodies
Supplier-Nr: APrEST70894

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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