Recombinant Human ZNF260 Protein

Tag: C-His. Modification: unmodified. Start Site: Thr131. End Site: Gly300. Coverage: 0.44. Isoelectric Point: 9.5. Core Sequence: TGTKPYACKE CGKAFNGKAY LTEHEKIHTG EKPFECNQCG RAFSQKQYLI KHQNIHTGKK PFKCSECGKA FSQKENLIIH QRIHTGEKPY ECKGCGKAFI QKSSLIRHQR SHTGEKPYTC KECGKAFSGK SNLTEHEKIH IGEKPYKCNE CGTIFRQKQY LIKHHNIHTG. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 95%, Rat - 95%, Pig - 94%, Cynomolgus monkey - 99%, Protein Function: Transcription factor that acts as a cardiac regulator and an effector of alpha1-adrenergic signaling. Binds to PE response elements (PERE) present in the promoter of genes such as ANF/NPPA and acts as a direct transcriptional activator of NPPA. Also acts as a cofactor with GATA4, a key cardiac regulator (By similarity) [The Uniprot Consortium]