Recombinant Human UGT3A1 Protein

Tag: C-His. Modification: unmodified. Start Site: His51. End Site: Asp140. Coverage: 0.19. Isoelectric Point: 7. Core Sequence: HNVTMLHQSG KFLIPDIKEE EKSYQVIRWF SPEDHQKRIK KHFDSYIETA LDGRKESEAL VKLMEIFGTQ CSYLLSRKDI MDSLKNENYD. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 49%, Cynomolgus monkey - 86%, Protein Function: UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity) [The Uniprot Consortium]