Recombinant Human TRIM50 protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-11602.20	20 µg		-	-	Request delivery time estimate		90.00€
ABS-PP-11602.100	100 µg		-	-	Request delivery time estimate		180.00€

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Protein function: E3 ubiquitin-protein ligase that ubiquitinates Beclin-1/BECN1 in a... more

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Product information "Recombinant Human TRIM50 protein"

Protein function: E3 ubiquitin-protein ligase that ubiquitinates Beclin-1/BECN1 in a 'Lys-63'-dependent manner enhancing its binding to ULK1. In turn, promotes starvation-induced autophagy activation. Interacts also with p62/SQSTM1 protein and thereby induces the formation and the autophagy clearance of aggresome-associated polyubiquitinated proteins through HDAC6 interaction. [The UniProt Consortium]

Keywords:	E3 ubiquitin-protein ligase TRIM50, RING-type E3 ubiquitin transferase TRIM50, Tripartite motif-containing protein 50, Recombinant Human TRIM50 protein
Supplier:	Absea
Supplier-Nr:	PP-11602

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	13.5 kD
Format:	Solution

Database Information

KEGG ID :	K12024 \| Matching products
UniProt ID :	Q86XT4 \| Matching products
Gene ID :	GeneID 135892 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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