Recombinant Human STRIP2 Protein

Tag: C-His. Modification: unmodified. Start Site: Gly11. End Site: His150. Coverage: 0.17. Isoelectric Point: 5.5. Core Sequence: GPPANGNGNG GGKGKQAAPK GREAFRSQRR ESEGSVDCPT LEFEYGDADG HAAELSELYS YTENLEFTNN RRCFEEDFKT QVQGKEWLEL EEDAQKAYIM GLLDRLEVVS RERRLKVARA VLYLAQGTFG ECDSEVDVLH. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 91%, Pig - 92%, Cynomolgus monkey - 100%, Protein Function: Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape (PubMed:21834987). Calmodulin-binding scaffolding protein which is the center of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation (PubMed:18782753) [The Uniprot Consortium]