Recombinant Human PSMD3 Protein

Tag: N-MBP & C-His. Modification: unmodified. Start Site: Thr391. End Site: Glu520. Coverage: 0.24. Isoelectric Point: 6. Core Sequence: TYTLIIRLRH NVIKTGVRMI SLSYSRISLA DIAQKLQLDS PEDAEFIVAK AIRDGVIEAS INHEKGYVQS KEMIDIYSTR EPQLAFHQRI SFCLDIHNMS VKAMRFPPKS YNKDLESAEE RREREQQDLE. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 100%, Rat - 34%, Pig - 100%, Cynomolgus monkey - 100%, Protein Function: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair [The Uniprot Consortium]