Recombinant Human PSMD13 Protein

Tag: N-MBP & C-His. Modification: unmodified. Start Site: Leu251. End Site: Gln370. Coverage: 0.34. Isoelectric Point: 6. Core Sequence: LKTAWGQQPD LAANEAQLLR KIQLLCLMEM TFTRPANHRQ LTFEEIAKSA KITVNEVELL VMKALSVGLV KGSIDEVDKR VHMTWVQPRV LDLQQIKGMK DRLEFWCTDV KSMEMLVEHQ. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 95%, Rat - 94%, Pig - 99%, Cynomolgus monkey - 99%, Protein Function: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair [The Uniprot Consortium]