Recombinant Human PIGX Protein

Tag: C-His. Modification: unmodified. Start Site: Glu101. End Site: Lys210. Coverage: 0.48. Isoelectric Point: 6. Core Sequence: ERNITEAVMV SENFDIEAPN YLSKESEVLI YARRDSQCID CFQAFLPVHC RYHRPHSEDG EASIVVNNPD LLMFCDQEFP ILKCWAHSEV AAPCALENED ICQWNKMKYK. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 79%, Rat - 79%, Pig - 81%, Cynomolgus monkey - 94%, Protein Function: Stabilizing subunit of the glycosylphosphatidylinositol-mannosyltransferase I complex which catalyzes the transfer of the first mannose, via an alpha-1,4 bond from a dolichol-phosphate-mannose (Dol-P-Man) to the glucosaminyl acyl phosphatidylinositol (GlcN-(acyl)PI) intermediate to generate alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol and participates in the sixth step of the glycosylphosphatidylinositol-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM [The Uniprot Consortium]