Recombinant Human PCB Protein

Tag: N-MBP & C-His. Modification: unmodified. Start Site: Glu381. End Site: Leu490. Coverage: 0.1. Isoelectric Point: 6. Core Sequence: EDPARSFQPD TGRIEVFRSG EGMGIRLDNA SAFQGAVISP HYDSLLVKVI AHGKDHPTAA TKMSRALAEF RVRGVKTNIA FLQNVLNNQQ FLAGTVDTQF IDENPELFQL. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 99%, Rat - 98%, Pig - 99%, Cynomolgus monkey - 98%, Protein Function: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate [The Uniprot Consortium]