Recombinant Human Mitochondrial Ferritin Protein

Tag: C-His. Modification: unmodified. Start Site: Asn71. End Site: Asp210. Coverage: 0.77. Isoelectric Point: 6.5. Core Sequence: NFHPDSEAAI NRQINLELYA SYVYLSMAYY FSRDDVALNN FSRYFLHQSR EETEHAEKLM RLQNQRGGRI RLQDIKKPEQ DDWESGLHAM ECALLLEKNV NQSLLELHAL ASDKGDPHLC DFLETYYLNE QVKSIKELGD. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 89%, Rat - 83%, Pig - 91%, Cynomolgus monkey - 96%, Protein Function: Catalyzes the oxidation of ferrous iron(II) to ferric iron(III) and stores iron in a soluble, non-toxic, readily available form (PubMed:11323407, PubMed:15201052). Important for iron homeostasis (PubMed:11323407, PubMed:15201052). Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (PubMed:11323407, PubMed:15201052) [The Uniprot Consortium]