Recombinant Human KIR2DS5 Protein

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-25659.20	20 µg		-	-	10 - 14 business days*		90.00€
ABS-PP-25659.100	100 µg		-	-	10 - 14 business days*		180.00€

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Tag: C-His. Modification: unmodified. Start Site: Leu131. End Site: Asn240. Coverage: 0.42.... more

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Product information "Recombinant Human KIR2DS5 Protein"

Tag: C-His. Modification: unmodified. Start Site: Leu131. End Site: Asn240. Coverage: 0.42. Isoelectric Point: 7. Core Sequence: LSAQPGPTVL AGESVTLSCS SRSSYDMYHL SREGEAHERR LPAGPKVNRT FQADFPLDPA THGGTYRCFG SFRDSPYEWS KSSDPLLVSV TGNSSNSWPS PTEPSSETGN. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 42%, Rat - 42%, Pig - 57%, Cynomolgus monkey - 81%, Protein Function: Activating natural killer (NK) receptor that recognizes C2 epitopes of HLA-C alleles. Bridging the innate and adaptive immune systems, NK cells express a number of cell surface receptors which either inhibit or stimulate their cytotoxicity (PubMed:18624290, PubMed:18682925, PubMed:28685972). Able to activate NK cells citotoxicity and cytokine production such as IFNG (PubMed:18624290, PubMed:24269691). Receptor functions are attenuated even lost in some alleles, such as KIR2DS5*002 represented in this entry (PubMed:28685972) [The Uniprot Consortium]

Keywords:	KIR2DS5, CD158 antigen-like family member G, Natural killer-associated transcript 9, Killer cell immunoglobulin-like receptor 2DS5
Supplier:	Absea
Supplier-Nr:	PP-25659

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	14.5 kD
Format:	Solution

Database Information

KEGG ID :	K07982 \| Matching products
UniProt ID :	Q14953 \| Matching products
Gene ID :	GeneID 3810 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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