Recombinant Human HYAL4 Protein

Tag: N-MBP & C-His. Modification: unmodified. Start Site: Ala51. End Site: Thr370. Coverage: 0.69. Isoelectric Point: 7. Core Sequence: AWNAPTDQCL IKYNLRLNLK MFPVIGSPLA KARGQNVTIF YVNRLGYYPW YTSQGVPING GLPQNISLQV HLEKADQDIN YYIPAEDFSG LAVIDWEYWR PQWARNWNSK DVYRQKSRKL ISDMGKNVSA TDIEYLAKVT FEESAKAFMK ETIKLGIKSR PKGLWGYYLY PDCHNYNVYA PNYSGSCPED EVLRNNELSW LWNSSAALYP SIGVWKSLGD SENILRFSKF RVHESMRIST MTSHDYALPV FVYTRLGYRD EPLFFLSKQD LVSTIGESAA LGAAGIVIWG DMNLTASKAN CTKVKQFVSS DLGSYIANVT. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 81%, Rat - 44%, Pig - 90%, Cynomolgus monkey - 97%, Protein Function: Endo-hyaluronidase that degrades hyaluronan to smaller oligosaccharide fragments. Also has chondroitin sulfate hydrolase activity, The best substrate being the galactosaminidic linkage in the sequence of a trisulfated tetrasaccharide [The Uniprot Consortium]