Recombinant Human FN3K Protein

Recombinant Human FN3K Protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-PP-23058-L.20 20 µg - -

10 - 15 business days*

115.00€
ABS-PP-23058-L.100 100 µg - -

10 - 15 business days*

205.00€
 
Tag: C-His. Modification: unmodified. Start Site: Met51. End Site: Gly240. Coverage: 0.65.... more
Product information "Recombinant Human FN3K Protein"
Tag: C-His. Modification: unmodified. Start Site: Met51. End Site: Gly240. Coverage: 0.65. Isoelectric Point: 6. Core Sequence: MFEGEVASLE ALRSTGLVRV PRPMKVIDLP GGGAAFVMEH LKMKSLSSQA SKLGEQMADL HLYNQKLREK LKEEENTVGR RGEGAEPQYV DKFGFHTVTC CGFIPQVNEW QDDWPTFFAR HRLQAQLDLI EKDYADREAR ELWSRLQVKI PDLFCGLEIV PALLHGDLWS GNVAEDDVGP IIYDPASFYG. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 90%, Pig - 89%, Cynomolgus monkey - 92%, Protein Function: Fructosamine-3-kinase involved in protein deglycation by mediating phosphorylation of fructoselysine residues on glycated proteins, to generate fructoselysine-3 phosphate (PubMed:11016445, PubMed:11522682, PubMed:11975663). Fructoselysine-3 phosphate adducts are unstable and decompose under physiological conditions (PubMed:11522682, PubMed:11975663). Involved in intracellular deglycation in erythrocytes (PubMed:11975663). Involved in the response to oxidative stress by mediating deglycation of NFE2L2/NRF2, glycation impairing NFE2L2/NRF2 function (By similarity). Also able to phosphorylate psicosamines and ribulosamines (PubMed:14633848) [The Uniprot Consortium]
Keywords: FN3K, Fructosamine-3-kinase, Protein-psicosamine 3-kinase FN3K, Protein-ribulosamine 3-kinase FN3K
Supplier: Absea
Supplier-Nr: PP-23058-L

Properties

Conjugate: No
Host: E.coli
Species reactivity: human
MW: 24 kD
Format: Lyophilized

Handling & Safety

Storage: -20°C (protect from light & moisture)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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