Recombinant Human FAAH2 Protein

Tag: C-His. Modification: unmodified. Start Site: Pro41. End Site: Asp150. Coverage: 0.22. Isoelectric Point: 10. Core Sequence: PRPVTEPLLL LSGMQLAKLI RQRKVKCIDV VQAYINRIKD VNPMINGIVK YRFEEAMKEA HAVDQKLAEK QEDEATLENK WPFLGVPLTV KEAFQLQGMP NSSGLMNRRD. Homologies: Highest protein sequence identity to the following orthologs: Cynomolgus monkey - 98%, Protein Function: Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corresponding fatty acids, thereby regulating the signaling functions of these molecules (PubMed:17015445, PubMed:19926788). Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates [The Uniprot Consortium]