Recombinant Human EPDR1 (C-6His)

Recombinant Human Mammalian Ependymin-related Protein 1 is produced by our Mammalian expression system and the target gene encoding Ala38-Ser223 is expressed with a 6His tag at the C-terminus. EPDR1 is a member of the ependymin family. EPDR1 is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. It may play a role in calcium-dependent cell adhesion. EPDR1 is glycosylated, and the orthologous mouse protein is localized to the lysosome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. Protein Function: Binds anionic lipids and gangliosides at acidic pH [The Uniprot Consortium]