Recombinant Human DBI Protein

Tag: N-MBP & C-His. Modification: unmodified. Start Site: Ser2. End Site: Ile87. Coverage: 1. Isoelectric Point: 5.5. Core Sequence: SQAEFEKAAE EVRHLKTKPS DEEMLFIYGH YKQATVGDIN TERPGMLDFT GKAKWDAWNE LKGTSKEDAM KAYINKVEEL KKKYGI. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 78%, Rat - 78%, Pig - 90%, Cynomolgus monkey - 92%, Protein Function: Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor [The Uniprot Consortium]