Recombinant Human C-Reactive Protein Protein

Tag: C-His. Modification: unmodified. Start Site: Gln19. End Site: Pro224. Coverage: 1. Isoelectric Point: 6.5. Core Sequence: QTDMSRKAFV FPKESDTSYV SLKAPLTKPL KAFTVCLHFY TELSSTRGYS IFSYATKRQD NEILIFWSKD IGYSFTVGGS EILFEVPEVT VAPVHICTSW ESASGIVEFW VDGKPRVRKS LKKGYTVGAE ASIILGQEQD SFGGNFEGSQ SLVGDIGNVN MWDFVLSPDE INTIYLGGPF SPNVLNWRAL KYEVQGEVFT KPQLWP. Homologies: Highest protein sequence identity to the following orthologs: Mouse - 71%, Rat - 67%, Pig - 75%, Cynomolgus monkey - 91%, Protein Function: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells [The Uniprot Consortium]