RBL1 PrEST Antigen

RBL1 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST86028.100 100 µl - -

7 - 10 business days*

264.00€
 
Protein function: Key regulator of entry into cell division (PubMed:17671431). Directly involved... more
Product information "RBL1 PrEST Antigen"
Protein function: Key regulator of entry into cell division (PubMed:17671431). Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation (PubMed:8319904). May act as a tumor suppressor (PubMed:8319904). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: p107, pRb1, RBL1, Retinoblastoma-like protein 1, 107 kDa retinoblastoma-associated protein
Supplier: Atlas Antibodies
Supplier-Nr: APrEST86028

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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