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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay10947-50 | 50 µg | - |
6 - 10 business days* |
554.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Retinoblastoma-binding protein 5 (RbBP5) is a ubiquitously expressed nuclear protein that... more
Product information "RbBP5 (human, recombinant)"
Retinoblastoma-binding protein 5 (RbBP5) is a ubiquitously expressed nuclear protein that contains WD40 repeat-like domains. RbBP5 binds directly to tumor suppressor retinoblastoma protein (RB) and regulates cell proliferation. Interaction of RbBP5 occurs preferentially with underphosphorylated RB through the E1A-binding pocket B. RbBP5 is also an important component of the multi-subunit SET1 lysine methyltransferase protein complex, which includes MLL1. RbBP5 interacts directly with WDR5 contributing to the activation of the MLL1 core protein complex. MLL1-4 protein complexes catalyze the di- and trimethylation of histone H3 at lysine 4 (H3K4me2/me3), leading to the maintenance of global H3K4 trimethylation.Synonyms: RBQ3, Retinoblastoma binding Protein 5, SWD1, Set1c WD40 repeat protein, homolog. Purity: >90%. Source: Recombinant protein expressed in E. coli. Amino Acids: 2-538 (full length). MW: 72.9 kDa. Formulation: (Request formulation change), 50 mM Tris, pH 8.0, containing 150 mM sodium chloride and 20% glycerol. License: SUMOpro tag was used under non-exclusive license from LifeSensors, Inc.. UniProt Accession #: Q15291.
Keywords: | RBQ3, RBBP5, RBBP-5, RBBP-5, Retinoblastoma-binding protein 5, Retinoblastoma-binding protein 5, Retinoblastoma-binding protein RBQ-3, Retinoblastoma-binding protein RBQ-3 |
Supplier: | Cayman Chemical |
Supplier-Nr: | 10947 |
Properties
Application: | Enzyme activity |
Conjugate: | No |
MW: | 72,9 kD |
Purity: | >90% |
Format: | Solution |
Database Information
KEGG ID : | K14961 | Matching products |
UniProt ID : | Q15291 | Matching products |
Gene ID | GeneID 5929 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: -80°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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