RAPGEF1 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-6455-L.20	20 µg	-	-	-	Request delivery time estimate		115.00€
ABS-PP-6455-L.100	100 µg	-	-	-	Request delivery time estimate		205.00€

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Protein function: Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and... more

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Product information "RAPGEF1 (human), recombinant protein"

Protein function: Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Involved in cell branching and adhesion mediated by BCAR1-CRK-RAPGEF1 signaling and activation of RAP1 (PubMed:12432078). Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth. [The UniProt Consortium]

Keywords:	Rap guanine nucleotide exchange factor 1, CRK SH3-binding GNRP, Guanine nucleotide-releasing factor 2, Protein C3G, Recombinant Human RAPGEF1 Protein
Supplier:	Absea
Supplier-Nr:	PP-6455-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	15 kD
Format:	Lyophilized

Database Information

KEGG ID :	K06277 \| Matching products
UniProt ID :	Q13905 \| Matching products
Gene ID :	GeneID 2889 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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