RANBP3 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-9208-L.20	20 µg		-	-	10 - 15 business days*		115.00€
ABS-PP-9208-L.100	100 µg		-	-	10 - 15 business days*		205.00€

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Protein function: Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export... more

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Product information "RANBP3 (human), recombinant protein"

Protein function: Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export. [The UniProt Consortium]

Keywords:	Ran-binding protein 3, RanBP3, Recombinant Human RANBP3 Protein
Supplier:	Absea
Supplier-Nr:	PP-9208-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	25 kD
Format:	Lyophilized

Database Information

KEGG ID :	K15304 \| Matching products
UniProt ID :	Q9H6Z4 \| Matching products
Gene ID :	GeneID 8498 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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