QKI (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-9134-L.20	20 µg	-	-	-	10 - 15 business days*		115.00€
ABS-PP-9134-L.100	100 µg	-	-	-	10 - 15 business days*		205.00€

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Protein function: RNA-binding protein that plays a central role in myelinization... more

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Product information "QKI (human), recombinant protein"

Protein function: RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5'-NACUAAY-N(1,20)-UAAY- 3' RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098). Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor. [The UniProt Consortium]

Keywords:	KH domain-containing RNA-binding protein QKI, Protein quaking, Hqk, HqkI, Recombinant Human QKI Protein
Supplier:	Absea
Supplier-Nr:	PP-9134-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	34 kD
Format:	Lyophilized

Database Information

KEGG ID :	K14945 \| Matching products
UniProt ID :	Q96PU8 \| Matching products
Gene ID :	GeneID 9444 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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