PSMD10 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-4687-L.20	20 µg	-	-	-	Request delivery time estimate		115.00€
ABS-PP-4687-L.100	100 µg	-	-	-	Request delivery time estimate		205.00€

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Protein function: Acts as a chaperone during the assembly of the 26S proteasome, specifically of... more

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Product information "PSMD10 (human), recombinant protein"

Protein function: Acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module. Independently of the proteasome, regulates EGF-induced AKT activation through inhibition of the RHOA/ROCK/PTEN pathway, leading to prolonged AKT activation. Plays an important role in RAS-induced tumorigenesis. [The UniProt Consortium]

Keywords:	26S proteasome non-ATPase regulatory subunit 10, 26S proteasome regulatory subunit p28, Gankyrin, p28(GANK), Recombinant Human PSMD10 Protein
Supplier:	Absea
Supplier-Nr:	PP-4687-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	25.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K06694 \| Matching products
UniProt ID :	O75832 \| Matching products
Gene ID :	GeneID 5716 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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