PSD-95/DLG4 Protein (recombinant human)

PSD-95/DLG4 Protein (recombinant human)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-RPCB0763.10 10 µg - - -

10 - 15 business days*

202.00€
 
Endotoxin level: < 1.0 EU/µg of the protein by LAL method. Protein function: Postsynaptic... more
Product information "PSD-95/DLG4 Protein (recombinant human)"
Endotoxin level: < 1.0 EU/µg of the protein by LAL method. Protein function: Postsynaptic scaffolding protein that plays a critical role in synaptogenesis and synaptic plasticity by providing a platform for the postsynaptic clustering of crucial synaptic proteins. Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression. [The UniProt Consortium]
Keywords: PSD95, SAP90, SAP-90, PSD-95, Disks large homolog 4, Synapse-associated protein 90, Postsynaptic density protein 95
Supplier: Assay Genie
Supplier-Nr: RPCB0763

Properties

Conjugate: No
Host: E.coli
Species reactivity: human
Purity: >95% (SDS-PAGE)

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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