Prostaglandin D Synthase (lipocalin-type, human recombinant)

Prostaglandin D Synthase (lipocalin-type, human recombinant)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10006788-250 250 µg -

3 - 10 business days*

494.00€
 
Prostaglandin D synthase (PGDS) catalyzes the isomerization of PGH2 to produce PGD2. PGD2 induces... more
Product information "Prostaglandin D Synthase (lipocalin-type, human recombinant)"
Prostaglandin D synthase (PGDS) catalyzes the isomerization of PGH2 to produce PGD2. PGD2 induces sleep, regulates nociception, inhibits platelet aggregation, and acts as an allergic mediator. Two distinct types of PGDS have been identified, namely the lipocalin-type enzyme and the hematopoietic enzyme. L-PGDS is localized in the central nervous system and male genital organs of various mammals and the human heart. This enzyme has been identified as beta-trace, which is a major protein in human cerebrospinal fluid. Cayman's L-PGDS (human recombinant) is a highly-purified GST-fusion protein isolated from an E. coli expression system. Cysteines 89 and 186 have been changed to alanines to prevent protein misfolding.
Keywords: PDS, PGDS, PGDS2, PTGDS, EC=5.3.99.2, Cerebrin-28, PGD2 synthase, Beta-trace protein, Prostaglandin-D2 synthase, Prostaglandin-H2 D-isomerase, Glutathione-independent PGD synthase, Lipocalin-type prostaglandin-D synthase
Supplier: Cayman Chemical
Supplier-Nr: 10006788-250

Properties

Application: Enzyme activity
Conjugate: No
MW: 46 kD
Purity: >85% estimated by SDS-PAGE
Format: Solution

Database Information

KEGG ID : K01830 | Find alternatives
UniProt ID : P41222 | Find alternatives

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -80°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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