PRC1 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-5894-L.20	20 µg	-	-	-	10 - 15 business days*		115.00€
ABS-PP-5894-L.100	100 µg	-	-	-	10 - 15 business days*		205.00€

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Protein function: Key regulator of cytokinesis that cross-links antiparrallel microtubules at an... more

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Product information "PRC1 (human), recombinant protein"

Protein function: Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436). [The UniProt Consortium]

Keywords:	Protein regulator of cytokinesis 1, Recombinant Human PRC1 Protein
Supplier:	Absea
Supplier-Nr:	PP-5894-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	28 kD
Format:	Lyophilized

Database Information

KEGG ID :	K16732 \| Matching products
UniProt ID :	O43663 \| Matching products
Gene ID :	GeneID 9055 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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