PR3 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PQ-226-L.20	20 µg		-	-	10 - 15 business days*		295.00€
ABS-PQ-226-L.100	100 µg		-	-	10 - 15 business days*		565.00€

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Protein function: Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and... more

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Product information "PR3 (human), recombinant protein"

Protein function: Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279). [The UniProt Consortium]

Keywords:	Myeloblastin, AGP7, C-ANCA antigen, Leukocyte proteinase 3, PR-3, PR3, Neutrophil proteinase 4, NP-4, P29, Wegener autoantigen, Recombinant Human PRTN3 Protein
Supplier:	Absea
Supplier-Nr:	PQ-226-L

Properties

Conjugate:	No
Host:	human cells
Species reactivity:	human
MW:	66.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K01350 \| Matching products
UniProt ID :	P24158 \| Matching products
Gene ID :	GeneID 5657 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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