PPP1R16B PrEST Antigen

PPP1R16B PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST95534.100 100 µl - -

7 - 10 business days*

264.00€
 
Protein function: Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of... more
Product information "PPP1R16B PrEST Antigen"
Protein function: Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function (PubMed:18586956). Involved in the regulation of the PI3K/AKT signaling pathway, angiogenesis and endothelial cell proliferation (PubMed:25007873). Regulates angiogenesis and endothelial cell proliferation through the control of ECE1 dephosphorylation, trafficking and activity. Protects the endothelial barrier from lipopolysaccharide (LPS)-induced vascular leakage. Involved in the regulation of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells (PubMed:16263087, PubMed:18586956). Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation (PubMed:18586956). Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1 (PubMed:16263087). Involved in the dephosphorylation of EEF1A1 (PubMed:26497934). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: ANKRD4, hTIMAP, PPP1R16B, CAAX box protein TIMAP, Ankyrin repeat domain-containing protein 4, TGF-beta-inhibited membrane-associated protein, Protein phosphatase 1 regulatory inhibitor subunit 16B
Supplier: Atlas Antibodies
Supplier-Nr: APrEST95534

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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