PLXNB2 PrEST Antigen

PLXNB2 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST73598.100 100 µl - -

7 - 10 business days*

264.00€
 
Protein function: Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important... more
Product information "PLXNB2 PrEST Antigen"
Protein function: Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Plays a role in glutamatergic synapse development and is required for SEMA4A- mediated excitatory synapse development. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton (PubMed:12183458). Plays a role in axon guidance, invasive growth and cell migration (PubMed:15184888). May modulate the activity of RAC1 and CDC42. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: MM1, PLXNB2, KIAA0315, Plexin-B2
Supplier: Atlas Antibodies
Supplier-Nr: APrEST73598

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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