PLCD4 (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-8201-L.20	20 µg		-	-	Request delivery time estimate		115.00€
ABS-PP-8201-L.100	100 µg		-	-	Request delivery time estimate		205.00€

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Protein function: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2... more

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Product information "PLCD4 (human), recombinant protein"

Protein function: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation. [The UniProt Consortium]

Keywords:	1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase delta-4, hPLCD4, Phosphoinositide phospholipase C-delta-4, Phospholipase C-delta-4, PLC-delta-4, Recombinant Human PLCD4 Protein
Supplier:	Absea
Supplier-Nr:	PP-8201-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	17.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K05857 \| Matching products
UniProt ID :	Q9BRC7 \| Matching products
Gene ID :	GeneID 84812 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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