PFKL (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-4780-L.20	20 µg	-	-	-	Request delivery time estimate		115.00€
ABS-PP-4780-L.100	100 µg	-	-	-	Request delivery time estimate		205.00€

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Protein function: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose... more

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Product information "PFKL (human), recombinant protein"

Protein function: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (PubMed:22923583). Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway. [The UniProt Consortium]

Keywords:	ATP-dependent 6-phosphofructokinase, liver type, ATP-PFK, PFK-L, 6-phosphofructokinase type B, Phosphofructo-1-kinase isozyme B, PFK-B, Phosphohexokinase, Recombinant Human PFKL Protein
Supplier:	Absea
Supplier-Nr:	PP-4780-L

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	44.5 kD
Format:	Lyophilized

Database Information

KEGG ID :	K00850 \| Matching products
UniProt ID :	P17858 \| Matching products
Gene ID :	GeneID 5211 \| Matching products

Handling & Safety

Storage:	-20°C (protect from light & moisture)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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