PDZD11, Recombinant, Human, aa1-140, His-Tag (PDZ Domain-containing Protein 11, AIPP1, PDZK11, PISP)

PDZD11, also known as AIPP1a, is a cytosolic protein which contains one PDZ (DHR) domain. This protein bears resemblance to members of the MALS / VELIS family of proteins. It contains but one PDZ domain that apparently interacts with the C-terminus of partner proteins. PDZD11 is ubiquitously expressed, and appears to target calcium and copper ATPases to basolateral cell membranes. It is a transiently interacting partner of the PMCA b-splice forms that may play a role in their sorting to or from the plasma membrane. Source: Recombinant protein corresponding to aa1-140 from human PDZD11 at N-terminal, fused to His-tag expressed in E.coli. Molecular Weight: ~18.5kD (163aa), AA Sequence: MGSSHHHHHH SSGLVPRGSH MGS SQLGIFISKV IPDSDAHRAG LQEGDQVLAV NDVDFQDIEH SKAVEILKTA REISMRVRFF PYNYHRQKER TVH MDSRIPY DDYPVVFLPA YENPPAWIPP HERVHHPDYN NELTQFLPRT ITLKKPPGAQ LGFNIRGGKA, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.