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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ATA-APrEST84143.100 | 100 µl | - | - |
7 - 10 business days* |
264.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the... more
Product information "PDE12 PrEST Antigen"
Protein function: Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. Degrades triphosphorylated 2-5A to produce AMP and ATP (PubMed:26055709). Also cleaves 3',5'-phosphodiester bond of oligoadenylates (PubMed:21666256, PubMed:30389976, PubMed:26055709). Plays a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme increases cellular 2-5A levels and decreases viral replication in cultured small-airway epithelial cells and Hela cells (PubMed:26055709). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
| Keywords: | 2-PDE, PDE12, 2'-PDE, Mitochondrial deadenylase, 2',5'-phosphodiesterase 12 |
| Supplier: | Atlas Antibodies |
| Supplier-Nr: | APrEST84143 |
Properties
| Application: | Control antigen |
| Conjugate: | No |
| Host: | E.coli |
| Species reactivity: | human |
Database Information
| KEGG ID : | K19612 | Matching products |
| UniProt ID : | Q6L8Q7 | Matching products |
| Gene ID : | GeneID 201626 | Matching products |
Handling & Safety
| Storage: | -20°C (avoid repeat freezing and thawing cycles) |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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