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Product information "PCIF1 (human), recombinant protein"
Protein function: Cap-specific adenosine methyltransferase that catalyzes formation of N(6),2'-O-dimethyladenosine cap (m6A(m)) by methylating the adenosine at the second transcribed position of capped mRNAs (PubMed:30467178, PubMed:30487554, PubMed:31279658, PubMed:31279659). Recruited to the early elongation complex of RNA polymerase II (RNAPII) via interaction with POLR2A and mediates formation of m6A(m) co- transcriptionally (PubMed:30467178). [The UniProt Consortium]
Keywords:
mRNA, 2'-O-methyladenosine-N(6)-)-methyltransferase, Cap-specific adenosine methyltransferase, CAPAM, hCAPAM, Phosphorylated CTD-interacting factor 1, hPCIF1, Protein phosphatase 1 regulatory subunit 121, Recombinant Human PCIF1 Protein
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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