OSBPL3 PrEST Antigen

OSBPL3 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST76113.100 100 µl - -

7 - 10 business days*

264.00€
 
Protein function: Phosphoinositide-binding protein which associates with both cell and... more
Product information "OSBPL3 PrEST Antigen"
Protein function: Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum (ER) membranes (PubMed:16143324). Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments (PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface (PubMed:18270267, PubMed:25447204). With VAPA, may regulate ER morphology (PubMed:16143324). Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion (PubMed:18270267). Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3 (PubMed:16143324). Also binds 25-hydroxycholesterol and cholesterol (PubMed:17428193). [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: ORP-3, OSBPL3, KIAA0704, OSBP-related protein 3, Oxysterol-binding protein-related protein 3
Supplier: Atlas Antibodies
Supplier-Nr: APrEST76113

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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