Optibumin(R) 25 - Recombinant human albumin

25% w/v Liquid Product Description: Optibumin(R) 25 is a high-purity, recombinant human serum albumin (rHSA) at 25% concentration, designed to replace plasma-derived HSA in cryopreservation, cell therapy, and biomanufacturing applications. As the first recombinant, animal-origin-free 25% HSA solution available in a ready-to-use liquid format, Optibumin 25 eliminates the risks associated with blood-derived albumin, ensuring batch-to-batch consistency, pathogen safety, and regulatory compliance. Protein function: Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (PubMed:19021548). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma. Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood. The rank order of affinity is zinc > calcium > magnesium. Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (PubMed:6234017). Does not prevent iron uptake by the bacterial siderophore aerobactin (PubMed:6234017). [The UniProt Consortium]