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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ABS-PP-1507-L.20 | 20 µg | - | - |
10 - 14 business days* |
115.00€
|
||
| ABS-PP-1507-L.100 | 100 µg | - | - |
10 - 14 business days* |
205.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of... more
Product information "NUDT5 (human), recombinant protein"
Protein function: Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate (PubMed:27257257). In absence of diphosphate, hydrolyzes with similar activities various modified nucleoside diphosphates such as ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP (PubMed:10567213, PubMed:10722730, PubMed:19699693, PubMed:21389046, PubMed:17052728). Can also hydrolyze other nucleotide sugars with low activity (PubMed:19699693, PubMed:21389046). In presence of diphosphate, mediates the synthesis of ATP in the nucleus by catalyzing the conversion of ADP-ribose to ATP and ribose 5-phosphate. Nuclear ATP synthesis takes place when dephosphorylated at Thr-45 (PubMed:27257257). Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming (PubMed:27257257). Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA. [The UniProt Consortium]
| Keywords: | ADP-sugar pyrophosphatase, 8-oxo-dGDP phosphatase, Nuclear ATP-synthesis protein NUDIX5, Nucleoside diphosphate-linked moiety X motif 5, Nudix motif 5, hNUDT5, YSA1H, Recombinant Human NUDT5 Protein |
| Supplier: | Absea |
| Supplier-Nr: | PP-1507-L |
Properties
| Conjugate: | No |
| Host: | E.coli |
| Species reactivity: | human |
| MW: | 25.5 kD |
| Format: | Lyophilized |
Database Information
| KEGG ID : | K13987 | Matching products |
| UniProt ID : | Q9UKK9 | Matching products |
| Gene ID : | GeneID 11164 | Matching products |
Handling & Safety
| Storage: | -20°C (protect from light & moisture) |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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