NSMCE4A (human), recombinant protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-PP-2846.20	20 µg	-	-	-	10 - 15 business days*		90.00€
ABS-PP-2846.100	100 µg	-	-	-	10 - 15 business days*		180.00€

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Protein function: Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand... more

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Product information "NSMCE4A (human), recombinant protein"

Protein function: Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Is involved in positive regulation of response to DNA damage stimulus. [The UniProt Consortium]

Keywords:	Non-structural maintenance of chromosomes element 4 homolog A, NS4EA, Non-SMC element 4 homolog A, Recombinant Human NSMCE4A Protein
Supplier:	Absea
Supplier-Nr:	PP-2846

Properties

Conjugate:	No
Host:	E.coli
Species reactivity:	human
MW:	27.5 kD
Format:	Solution

Database Information

KEGG ID :	K22825 \| Matching products
UniProt ID :	Q9NXX6 \| Matching products
Gene ID :	GeneID 54780 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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